The Ultrasonic (US) technique is used in the present work as an eco-friendly method for the synthesis of (5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide derivatives. A simple and efficient method has been described for the alkylation of (5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide (1). Besides the IR and NMR spectra, the regioselectivity of the N-alkylation is chemically achieved. Furthermore, fusion of sodium salt of 1 with ethyl bromide in DMF as solvent using ultrasound irradiation as a source of power afforded (1,3-diethyl-5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide (9).
Amer, A., Ahmed, D., & Moustafa, A. (2024). Eco-friendly and Regiospecific synthesis of Novel (5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide Derivatives. Sohag Journal of Sciences, 9(1), 64-68. doi: 10.21608/sjsci.2023.232963.1120
MLA
Amer A. Amer; Doaa H. Ahmed; Amr H. Moustafa. "Eco-friendly and Regiospecific synthesis of Novel (5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide Derivatives", Sohag Journal of Sciences, 9, 1, 2024, 64-68. doi: 10.21608/sjsci.2023.232963.1120
HARVARD
Amer, A., Ahmed, D., Moustafa, A. (2024). 'Eco-friendly and Regiospecific synthesis of Novel (5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide Derivatives', Sohag Journal of Sciences, 9(1), pp. 64-68. doi: 10.21608/sjsci.2023.232963.1120
VANCOUVER
Amer, A., Ahmed, D., Moustafa, A. Eco-friendly and Regiospecific synthesis of Novel (5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide Derivatives. Sohag Journal of Sciences, 2024; 9(1): 64-68. doi: 10.21608/sjsci.2023.232963.1120