Eco-friendly and Regiospecific synthesis of Novel (5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide Derivatives

Document Type : Regular Articles

Authors

1 Department of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt.

2 Faculty of Science, King Salman International University, Ras Sudr, Sinai 46612, Egypt.

Abstract

The Ultrasonic (US) technique is used in the present work as an eco-friendly method for the synthesis of (5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide derivatives. A simple and efficient method has been described for the alkylation of (5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide (1). Besides the IR and NMR spectra, the regioselectivity of the N-alkylation is chemically achieved. Furthermore, fusion of sodium salt of 1 with ethyl bromide in DMF as solvent using ultrasound irradiation as a source of power afforded (1,3-diethyl-5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide (9).

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