Synthesis, Characterization, and PASSS Inet Prediction of New Polyesters

Document Type : Regular Articles

Authors

1 Chemistry Department, Faculty of Science, Sohag University, Sohag 82524, Egypt

2 Polymer Research Laboratory, Chemistry Department, Faculty of Science, Assiut University, Assiut 71516, Egypt

Abstract

The interfacial polycondensation of indazole monomers 3 and 4 with various aromatic and aliphatic acid chlorides, including isophthaloyl-, terephthaloyl-, adipoyl-, and sebacoyl chloride, gave polyesters 5a-d and 6a-d containing an indazole moiety. The generated polyesters were categorized using elemental analysis, IR, 1H­NMR, and MS spectra; XRD and Thermal Gravimetry analysis (TGA) examinations. Prediction of inflammatory biological behavior of selected polyesters using PASS Inet at Pa < 0.70, giving a high probability of anti-Gluconate 2-dehydrogenase (acceptor) inhibitor.

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Sohag Journal of Sciences
Volume 8, Issue 1
January 2023
Pages 15-20

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